History of Xenophage

Xenophage is a Solar Exotic Machine Gun with an anti-Unstoppable profile. Its intrinsic perk, Pyrotoxin Rounds, fires high-powered explosive ammunition. Lore-wise it is the first known weapon to use a Guardian's soul: that of Omar Agah, a Titan transformed by Hive experimentation, visible as a crystal during reload.

Acquisition

• Complete "The Journey" Exotic Quest, released with Destiny 2: Shadowkeep, which includes puzzle solving and a run of the Pit of Heresy Dungeon.

Catalyst

Added in June 2026. PC Gamer’s June 10, 2026 table lists a random drop from the Pit of Heresy dungeon and the Chain Reaction and Rampage perks. The source does not identify a specific boss, checkpoint, or reset method, and later route changes were not independently confirmed. Complete the catalyst’s in-game target-defeat objective to unlock it.

Sources

• Xenophage - Destinypedia — Destinypedia; Existing source retained for the acquisition and overview details above.
• How to get the Xenophage Exotic Catalyst in Destiny 2 — Shacknews; Existing source retained for the acquisition and overview details above.
• All 26 new catalysts in Destiny 2's final update — PC Gamer; June 10, 2026 catalyst perk and acquisition table.
• Destiny 2 Update 9.7.0 — Bungie; June 9, 2026 update date and Pantheon 2.0 context.
• Xenophage Catalyst — Reference; Manifest-derived catalyst traits; direct page access was unavailable during this review, so no exact completion count is stated.
• These NEW Catalysts Are INSANE... | Destiny 2 Monument of Triumph — Aztecross; Aztecross creator overview of the June 2026 Exotic catalyst additions.